| Gene Information | |
|---|---|
| Gene Name | TMEM106C |
| Organism | Homo sapiens (Human) |
| Gene Length | 250 |
| Protein Names | Transmembrane protein 106C (Endoplasmic reticulum membrane protein overexpressed in cancer) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000134291 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BVX2 |
| Gene Card | TMEM106C |
| Uniprot ID | Q9BVX2 |
| Pfam | PF07092 |
| In ASD | no |
| Allosteric Prediction | no (-1.645665369) |
| Ortholog in Animals | Alpaca_ TMEM106C ( ortholog_one2one ) Dog_ TMEM106C ( ortholog_one2one ) GuineaPig_ TMEM106C ( ortholog_one2one ) Macaque_ TMEM106C ( ortholog_one2one ) Mouse_ Tmem106c ( ortholog_one2one ) Rat_ Tmem106c ( ortholog_one2one ) |
| Ohnologs | TMEM106A, TMEM106B |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35000511 rs2286025 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|Ref.1}; Multi-pass membrane protein {ECO:0000269|Ref.1}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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