| Gene Information | |
|---|---|
| Gene Name | ACTR3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 418 |
| Protein Names | Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000133627 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9P1U1 |
| Gene Card | ACTR3B |
| Uniprot ID | Q9P1U1 |
| Pfam | PF00022 |
| In ASD | no |
| Allosteric Prediction | no (-0.597305176) |
| Ortholog in Animals | Alpaca_ ACTR3B ( ortholog_one2one ) Dog_ ACTR3B ( ortholog_one2many ) Macaque_ ACTR3B ( ortholog_one2many ) Mouse_ Actr3b ( ortholog_one2many ) Rat_ Actr3b ( ortholog_one2many ) |
| Ohnologs | ACTR3 |
| Paralogs | ACTR3C, ACTC1, ACTBL2, ACTR1A, ACTB, ACTG1, ACTR5, ACTL9, ACTR3, ACTL7A, ACTL7B, ACTL8, ACTA1, ACTL6B, ACTRT2, ACTR8, ACTR1B, ACTL6A, ACTR2, ACTR6, ACTRT1, ACTRT3, ACTL10, ACTG2, ACTA2, ACTR10 |
| Tissue | NA |
| Tissue Specificity | Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential. {ECO:0000269|PubMed:10806390, ECO:0000269|PubMed:11162478}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.349370(Rat);0.101401(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2260545 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection {ECO:0000250}. |
| Mouse PG classification | NA |
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