| Gene Information | |
|---|---|
| Gene Name | ID2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 134 |
| Protein Names | DNA-binding protein inhibitor ID-2 (Class B basic helix-loop-helix protein 26) (bHLHb26) (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000115738 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q02363 |
| Gene Card | ID2 |
| Uniprot ID | Q02363 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-0.419015465) |
| Ortholog in Animals | Alpaca_ ID2 ( ortholog_one2one ) Dog_ ID2 ( ortholog_one2one ) GuineaPig_ ID2 ( ortholog_one2one ) Macaque_ ID2 ( ortholog_one2one ) Mouse_ Id2 ( ortholog_one2one ) Pig_ ID2 ( ortholog_one2one ) Rat_ Id2 ( ortholog_one2one ) Rabbit_ ID2 ( ortholog_one2one ) |
| Ohnologs | ID1, ID4, ID3 |
| Paralogs | ID1, ID3, ID4 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in early fetal tissues, including those of the central nervous system. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.02(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4AYA (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P41136}. Nucleus {ECO:0000250|UniProtKB:P41136}. |
| Mouse PG classification | NA |
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