Gene Information
Gene NameMED16
OrganismHomo sapiens (Human)
Gene Length877
Protein NamesMediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000175221 )
3 ( ENSG00000282092 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9Y2X0
Gene CardMED16
Uniprot IDQ9Y2X0
PfamPF11635
In ASDno
Allosteric Predictionno (-0.461802411)
Ortholog in AnimalsAlpaca_ MED16 ( ortholog_one2one )
Dog_ MED16 ( ortholog_one2one )
GuineaPig_ MED16 ( ortholog_one2one )
Macaque_ MED16 ( ortholog_one2one )
Mouse_ Med16 ( ortholog_one2one )
Pig_ MED16 ( ortholog_one2one )
Rat_ Med16 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.094816(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7EMF  (EM  3.50A  7ENA  (EM  4.07A  7ENC  (EM  4.13A  7ENJ  (EM  4.40A  7LBM  (EM  4.80A 
DBSNP rs34859566  rs13090 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
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