| Gene Information | |
|---|---|
| Gene Name | TMCO3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 677 |
| Protein Names | Transmembrane and coiled-coil domain-containing protein 3 (Putative LAG1-interacting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000150403 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q6UWJ1 |
| Gene Card | TMCO3 |
| Uniprot ID | Q6UWJ1 |
| Pfam | PF00999 |
| In ASD | no |
| Allosteric Prediction | no (-0.782559717) |
| Ortholog in Animals | Alpaca_ TMCO3 ( ortholog_one2one ) Dog_ TMCO3 ( ortholog_one2one ) GuineaPig_ TMCO3 ( ortholog_one2one ) Macaque_ TMCO3 ( ortholog_one2one ) Mouse_ Tmco3 ( ortholog_one2one ) Pig_ TMCO3 ( ortholog_one2one ) Rat_ Tmco3 ( ortholog_one2one ) Rabbit_ TMCO3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the cornea, lens capsule and choroid-retinal pigment epithelium (at protein level). {ECO:0000269|PubMed:27484837}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs185071949 rs2260335 rs7319493 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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