| Gene Information | |
|---|---|
| Gene Name | TMC5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1006 |
| Protein Names | Transmembrane channel-like protein 5 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000103534 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6UXY8 |
| Gene Card | TMC5 |
| Uniprot ID | Q6UXY8 |
| Pfam | PF07810 |
| In ASD | no |
| Allosteric Prediction | no (-1.6726009) |
| Ortholog in Animals | Alpaca_ TMC5 ( ortholog_one2one ) Dog_ TMC5 ( ortholog_one2one ) GuineaPig_ TMC5 ( ortholog_one2one ) Macaque_ TMC5 ( ortholog_one2one ) Mouse_ Tmc5 ( ortholog_one2one ) Pig_ TMC5 ( ortholog_one2one ) Rat_ Tmc5 ( ortholog_one2one ) Rabbit_ TMC5 ( ortholog_one2one ) |
| Ohnologs | TMC6, TMC4, TMC8 |
| Paralogs | TMC6, TMC8, TMC7, TMC4, TMC2, TMC1, TMC3 |
| Tissue | small.intestine, lung, minor.salivary.gland, small.intestine.Peyers.patch, stomach, transverse.colon |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16972013 rs36019638 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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