| Gene Information | |
|---|---|
| Gene Name | TMC4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 712 |
| Protein Names | Transmembrane channel-like protein 4 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000167608 ) 3 ( ENSG00000273722 ) 3 ( ENSG00000274384 ) 3 ( ENSG00000274873 ) 3 ( ENSG00000274905 ) 3 ( ENSG00000276260 ) 3 ( ENSG00000277667 ) 3 ( ENSG00000277789 ) 3 ( ENSG00000277996 ) 3 ( ENSG00000278363 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q7Z404 |
| Gene Card | TMC4 |
| Uniprot ID | Q7Z404 |
| Pfam | PF07810 |
| In ASD | yes |
| Allosteric Prediction | no (-1.217033286) |
| Ortholog in Animals | Alpaca_ TMC4 ( ortholog_one2many ) Dog_ TMC4 ( ortholog_one2one ) GuineaPig_ TMC4 ( ortholog_one2one ) Macaque_ TMC4 ( ortholog_one2one ) Mouse_ Tmc4 ( ortholog_one2one ) Pig_ TMC4 ( ortholog_one2one ) Rat_ Tmc4 ( ortholog_one2one ) |
| Ohnologs | TMC5, TMC6, TMC8, TMC7 |
| Paralogs | TMC7, TMC8, TMC6, TMC5, TMC2, TMC1, TMC3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs641738 rs36657 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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