| Gene Information | |
|---|---|
| Gene Name | TMBIM6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 237 |
| Protein Names | Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000139644 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P55061 |
| Gene Card | TMBIM6 |
| Uniprot ID | P55061 |
| Pfam | PF01027 |
| In ASD | no |
| Allosteric Prediction | no (-0.823270223) |
| Ortholog in Animals | Alpaca_ TMBIM6 ( ortholog_one2one ) Dog_ TMBIM6 ( ortholog_one2many ) GuineaPig_ TMBIM6 ( ortholog_one2one ) Macaque_ TMBIM6 ( ortholog_one2one ) Mouse_ Tmbim6 ( ortholog_one2one ) Pig_ TMBIM6 ( ortholog_one2one ) Rat_ Tmbim6 ( ortholog_one2one ) Rabbit_ TMBIM6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TMBIM1, GRINA, FAIM2, GHITM, TMBIM4 |
| Tissue | NA |
| Tissue Specificity | Highly abundant in testis. {ECO:0000269|PubMed:8530040}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21075086, ECO:0000269|PubMed:22128171}; Multi-pass membrane protein {ECO:0000269|PubMed:21075086, ECO:0000269|PubMed:22128171}. |
| Mouse PG classification | NA |
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