| Gene Information | |
|---|---|
| Gene Name | SLC2A8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 477 |
| Protein Names | Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000136856 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NY64 |
| Gene Card | SLC2A8 |
| Uniprot ID | Q9NY64 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | yes (0.543951687) |
| Ortholog in Animals | Alpaca_ SLC2A8 ( ortholog_one2one ) Dog_ SLC2A8 ( ortholog_one2one ) GuineaPig_ SLC2A8 ( ortholog_one2one ) Macaque_ SLC2A8 ( ortholog_one2one ) Mouse_ Slc2a8 ( ortholog_one2one ) Pig_ SLC2A8 ( ortholog_one2one ) Rat_ Slc2a8 ( ortholog_one2one ) Rabbit_ SLC2A8 ( ortholog_one2one ) |
| Ohnologs | SLC2A6 |
| Paralogs | SLC2A7, SLC2A6, SLC2A5, SLC2A11, SLC2A2, SLC2A1, SLC2A4, SLC2A3, SLC2A14, SLC2A13, SLC2A9, SLC2A12, SLC2A10 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues. {ECO:0000269|PubMed:10821868}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34064803 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9JJZ1}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9JJZ1}; Multi-pass membrane protein {ECO:0000255}. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration. {ECO:0000250|UniProtKB:Q9JJZ1}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |