Gene Information
Gene NameTM2D1
OrganismHomo sapiens (Human)
Gene Length207
Protein NamesTM2 domain-containing protein 1 (Amyloid-beta-binding protein) (hBBP)
Target NameNA
Target TypeNA
Gene Age1064 ( ENSG00000162604 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9BX74
Gene CardTM2D1
Uniprot IDQ9BX74
PfamPF05154
In ASDno
Allosteric Predictionno (-1.566392796)
Ortholog in AnimalsAlpaca_ TM2D1 ( ortholog_one2one )
Dog_ TM2D1 ( ortholog_one2one )
GuineaPig_ TM2D1 ( ortholog_one2one )
Macaque_ TM2D1 ( ortholog_one2one )
Mouse_ Tm2d1 ( ortholog_one2one )
Pig_ TM2D1 ( ortholog_one2one )
Rat_ Tm2d1 ( ortholog_one2one )
Rabbit_ TM2D1 ( ortholog_one2one )
OhnologsNA
ParalogsTM2D3, TM2D2
TissueNA
Tissue SpecificityWidely expressed. {ECO:0000269|PubMed:11278849}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000269|PubMed:11278849};
Multi-pass membrane protein {ECO:0000269|PubMed:11278849}.
Mouse PG classificationNA
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