| Gene Information | |
|---|---|
| Gene Name | TLX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 284 |
| Protein Names | T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000115297 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O43763 |
| Gene Card | TLX2 |
| Uniprot ID | O43763 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-0.788960648) |
| Ortholog in Animals | Alpaca_ TLX2 ( ortholog_one2one ) Dog_ TLX2 ( ortholog_one2one ) GuineaPig_ TLX2 ( ortholog_one2one ) Macaque_ TLX2 ( ortholog_one2one ) Mouse_ Tlx2 ( ortholog_one2one ) Pig_ TLX2 ( ortholog_one2one ) Rat_ Tlx2 ( ortholog_one2one ) Rabbit_ TLX2 ( ortholog_one2one ) |
| Ohnologs | TLX1, TLX3 |
| Paralogs | HOXA1, HOXD10, HOXC4, HOXD4, HOXA4, HOXD11, HOXC10, HOXA6, TLX3, HOXA10, HOXB3, HOXD13, HOXD9, HOXB4, HOXD1, HOXB7, HOXD8, HOXC5, HOXD3, HOXA13, HOXB8, HOXC9, HOXA3, HOXA5, HOXC11, HOXB2, HOXD12, GSX2, HOXB5, HOXB9, HOXB1, TLX1, PDX1, HOXA2, HOXA11, HOXC6, HOXA7, HOXB13, HOXC8, HOXC12, HOXC13, HOXB6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3A03 (X-ray 1.54A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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