| Gene Information | |
|---|---|
| Gene Name | TLX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 330 |
| Protein Names | T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000107807 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P31314 |
| Gene Card | TLX1 |
| Uniprot ID | P31314 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-1.021220865) |
| Ortholog in Animals | Alpaca_ TLX1 ( ortholog_one2one ) Dog_ TLX1 ( ortholog_one2one ) GuineaPig_ TLX1 ( ortholog_one2one ) Macaque_ TLX1 ( ortholog_one2one ) Mouse_ Tlx1 ( ortholog_one2one ) Pig_ TLX1 ( ortholog_one2one ) Rat_ Tlx1 ( ortholog_one2one ) Rabbit_ TLX1 ( ortholog_one2one ) |
| Ohnologs | TLX2, TLX3 |
| Paralogs | HOXA1, HOXD10, HOXC4, HOXD4, HOXA4, HOXD11, HOXC10, HOXA6, TLX3, HOXA10, HOXB3, HOXD13, HOXD9, HOXB4, HOXD1, HOXB7, HOXD8, HOXC5, HOXD3, HOXA13, HOXB8, HOXC9, HOXA3, HOXA5, HOXC11, HOXB2, HOXD12, GSX2, HOXB5, HOXB9, HOXB1, TLX2, PDX1, HOXA2, HOXA11, HOXC6, HOXA7, HOXB13, HOXC8, HOXC12, HOXC13, HOXB6 |
| Tissue | spleen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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