Gene Information
Gene NameTLT2
OrganismHomo sapiens (Human)
Gene Length321
Protein NamesTrem-like transcript 2 protein (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ5T2D2
Gene CardTREML2
Uniprot IDQ5T2D2
PfamNA
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityDetected in cultured B-cells, T-cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:18650384}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs4418164  rs35512890  rs3747742  rs35521209 
Subcellular location [CC]Cell membrane {ECO:0000250};
Single-pass type I membrane protein {ECO:0000250}.
Mouse PG classificationNA
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