| Gene Information | |
|---|---|
| Gene Name | ABRAXAS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 409 |
| Protein Names | BRCA1-A complex subunit Abraxas 1 (Coiled-coil domain-containing protein 98) (Protein FAM175A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000163322 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6UWZ7 |
| Gene Card | ABRAXAS1 |
| Uniprot ID | Q6UWZ7 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.009751039) |
| Ortholog in Animals | Alpaca_ ABRAXAS1 ( ortholog_one2one ) Dog_ ABRAXAS1 ( ortholog_one2one ) GuineaPig_ ABRAXAS1 ( ortholog_one2one ) Macaque_ ABRAXAS1 ( ortholog_one2one ) Mouse_ Abraxas1 ( ortholog_one2one ) Pig_ ABRAXAS1 ( ortholog_one2one ) Rat_ Abraxas1 ( ortholog_one2one ) Rabbit_ ABRAXAS1 ( ortholog_one2one ) |
| Ohnologs | ABRAXAS2 |
| Paralogs | ABRAXAS2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.419556(Rat);0.080000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4JLU (X-ray 3.50A ) 4U4A (X-ray 3.51A ) 4Y18 (X-ray 3.50A ) 4Y2G (X-ray 2.50A ) |
| DBSNP | rs752929794 rs12642536 rs201627097 rs13125836 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:17525340, ECO:0000269|PubMed:17643121, ECO:0000269|PubMed:17643122}. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs). {ECO:0000305}. |
| Mouse PG classification | NA |
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