| Gene Information | |
|---|---|
| Gene Name | TLE5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 197 |
| Protein Names | TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000104964 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q08117 |
| Gene Card | TLE5 |
| Uniprot ID | Q08117 |
| Pfam | PF03920 |
| In ASD | no |
| Allosteric Prediction | no (-0.635996147) |
| Ortholog in Animals | Alpaca_ TLE5 ( ortholog_one2one ) Dog_ TLE5 ( ortholog_one2one ) GuineaPig_ TLE5 ( ortholog_one2one ) Mouse_ Tle5 ( ortholog_one2one ) Pig_ TLE5 ( ortholog_one2one ) Rat_ Tle5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TLE6, TLE7, TLE2, TLE1, TLE4, TLE3 |
| Tissue | NA |
| Tissue Specificity | Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1802578 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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