Gene Information
Gene NameTLE4
OrganismHomo sapiens (Human)
Gene Length773
Protein NamesTransducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000106829 )
Evolutionary StageEukaryota
AlphaFoldDBQ04727
Gene CardTLE4
Uniprot IDQ04727
PfamPF03920; PF00400
In ASDno
Allosteric Predictionno (-0.692881092)
Ortholog in AnimalsAlpaca_ TLE4 ( ortholog_one2one )
Dog_ TLE4 ( ortholog_one2one )
GuineaPig_ TLE4 ( ortholog_one2one )
Macaque_ TLE4 ( ortholog_one2one )
Mouse_ Tle4 ( ortholog_one2one )
Pig_ TLE4 ( ortholog_one2one )
Rat_ Tle4 ( ortholog_one2one )
Rabbit_ TLE4 ( ortholog_one2one )
OhnologsTLE2, TLE3
ParalogsTLE1, TLE6, TLE5, TLE7, TLE2, TLE3
Tissuetestis
Tissue SpecificityIn all tissues examined, mostly in brain, and muscle.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.034483(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus.
Mouse PG classificationNA
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