| Gene Information | |
|---|---|
| Gene Name | TLE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 743 |
| Protein Names | Transducin-like enhancer protein 2 (Enhancer of split groucho-like protein 2) (ESG2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000065717 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q04725 |
| Gene Card | TLE2 |
| Uniprot ID | Q04725 |
| Pfam | PF03920; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.801482467) |
| Ortholog in Animals | Alpaca_ TLE2 ( ortholog_one2one ) Dog_ TLE2 ( ortholog_one2one ) GuineaPig_ TLE2 ( ortholog_one2one ) Macaque_ TLE2 ( ortholog_one2one ) Mouse_ Tle2 ( ortholog_one2one ) Pig_ TLE2 ( ortholog_one2one ) Rat_ Tle2 ( ortholog_one2one ) |
| Ohnologs | TLE4, TLE3, TLE1 |
| Paralogs | TLE6, TLE5, TLE7, TLE1, TLE4, TLE3 |
| Tissue | NA |
| Tissue Specificity | In all tissues examined, mostly in heart, brain, and muscle. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs199788562 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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