| Gene Information | |
|---|---|
| Gene Name | LUC7L3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 432 |
| Protein Names | Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000108848 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95232 |
| Gene Card | LUC7L3 |
| Uniprot ID | O95232 |
| Pfam | PF03194 |
| In ASD | no |
| Allosteric Prediction | no (-1.241721496) |
| Ortholog in Animals | Alpaca_ LUC7L3 ( ortholog_one2one ) Dog_ LUC7L3 ( ortholog_one2one ) GuineaPig_ LUC7L3 ( ortholog_one2one ) Macaque_ LUC7L3 ( ortholog_one2one ) Mouse_ Luc7l3 ( ortholog_one2one ) Pig_ LUC7L3 ( ortholog_one2one ) Rat_ Luc7l3 ( ortholog_one2one ) Rabbit_ LUC7L3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LUC7L, LUC7L2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung. {ECO:0000269|PubMed:10631324, ECO:0000269|PubMed:16462885}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:10631324, ECO:0000269|PubMed:12565863}. Note=The subnuclear localization is affected by cisplatin. |
| Mouse PG classification | NA |
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