| Gene Information | |
|---|---|
| Gene Name | TKT |
| Organism | Homo sapiens (Human) |
| Gene Length | 623 |
| Protein Names | Transketolase (TK) (EC 2.2.1.1) |
| Target Name | transketolase |
| Target Type | Literature-reported target |
| Gene Age | 454 ( ENSG00000163931 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P29401 |
| Gene Card | TKT |
| Uniprot ID | P29401 |
| Pfam | PF02779; PF02780; PF00456 |
| In ASD | no |
| Allosteric Prediction | yes (0.673782811) |
| Ortholog in Animals | Alpaca_ TKT ( ortholog_one2one ) Dog_ TKT ( ortholog_one2one ) GuineaPig_ TKT ( ortholog_one2one ) Macaque_ TKT ( ortholog_one2one ) Mouse_ Tkt ( ortholog_one2one ) Pig_ TKT ( ortholog_one2one ) Rat_ Tkt ( ortholog_one2one ) Rabbit_ TKT ( ortholog_one2one ) |
| Ohnologs | TKTL1, TKTL2 |
| Paralogs | BCKDHB, PDHB, TKTL2, TKTL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.058598(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3MOS (X-ray 1.75A ) 3OOY (X-ray 2.05A ) 4KXU (X-ray 0.98A ) 4KXV (X-ray 0.97A ) 4KXW (X-ray 0.97A ) 4KXX (X-ray 1.03A ) 4KXY (X-ray 1.26A ) 6HA3 (X-ray 1.08A ) 6HAD (X-ray 1.04A ) 6RJB (X-ray 1.15A ) |
| DBSNP | rs17052920 rs782092363 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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