| Gene Information | |
|---|---|
| Gene Name | TKS4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 911 |
| Protein Names | SH3 and PX domain-containing protein 2B (Adapter protein HOFI) (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | A1X283 |
| Gene Card | SH3PXD2B |
| Uniprot ID | A1X283 |
| Pfam | PF00787; PF00018; PF07653 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in fibroblasts. {ECO:0000269|PubMed:20137777}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs267607046 rs6880739 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell projection, podosome {ECO:0000250}. Note=Cytoplasmic in normal cells and localizes to podosomes in SRC-transformed cells. {ECO:0000250}. |
| Mouse PG classification | NA |
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