| Gene Information | |
|---|---|
| Gene Name | TKR |
| Organism | Homo sapiens (Human) |
| Gene Length | 596 |
| Protein Names | Transketolase-like protein 1 (EC 2.2.1.1) (Transketolase 2) (TK 2) (Transketolase-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P51854 |
| Gene Card | TKTL1 |
| Uniprot ID | P51854 |
| Pfam | PF02779; PF02780; PF00456 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in fetal and adult heart, brain, lung, liver, and kidney, and in adult placenta, skeletal muscle and pancreas. Up-regulated in various epithelial tumors. {ECO:0000269|PubMed:15991799, ECO:0000269|PubMed:16465194, ECO:0000269|PubMed:16969476, ECO:0000269|PubMed:8838793}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.034783(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17855509 rs17852259 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16465194, ECO:0000269|PubMed:16969476}. Nucleus {ECO:0000269|PubMed:16465194, ECO:0000269|PubMed:16969476}. Note=Predominantly cytoplasmic and to a lesser extent also nuclear (PubMed:16969476). |
| Mouse PG classification | NA |
| click here to return to the previous page | |