| Gene Information | |
|---|---|
| Gene Name | TK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 265 |
| Protein Names | Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (2'-deoxyuridine kinase TK2) (EC 2.7.1.74) (Deoxycytidine kinase TK2) (EC 2.7.1.-) (Mt-TK) |
| Target Name | thymidine kinase 2, mitochondrial |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000166548 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O00142 |
| Gene Card | TK2 |
| Uniprot ID | O00142 |
| Pfam | PF01712 |
| In ASD | no |
| Allosteric Prediction | no (-0.148424592) |
| Ortholog in Animals | Alpaca_ TK2 ( ortholog_one2one ) Dog_ TK2 ( ortholog_one2one ) GuineaPig_ TK2 ( ortholog_one2one ) Macaque_ TK2 ( ortholog_one2one ) Mouse_ Tk2 ( ortholog_one2one ) Pig_ TK2 ( ortholog_one2one ) Rat_ Tk2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DCK, NDUFA10, DGUOK |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in liver, pancreas, muscle, and brain. {ECO:0000269|PubMed:9079672}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs137854432 rs281865487 rs137854431 rs137854429 rs281865494 rs137886900 rs281865495 rs281865496 rs137854430 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:9989599}. |
| Mouse PG classification | NA |
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