| Gene Information | |
|---|---|
| Gene Name | RNF20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 975 |
| Protein Names | E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000155827 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5VTR2 |
| Gene Card | RNF20 |
| Uniprot ID | Q5VTR2 |
| Pfam | PF00097 |
| In ASD | no |
| Allosteric Prediction | no (-0.092901982) |
| Ortholog in Animals | Alpaca_ RNF20 ( ortholog_one2one ) Dog_ RNF20 ( ortholog_one2one ) GuineaPig_ RNF20 ( ortholog_one2one ) Macaque_ RNF20 ( ortholog_one2one ) Mouse_ Rnf20 ( ortholog_one2one ) Pig_ RNF20 ( ortholog_one2one ) Rat_ Rnf20 ( ortholog_one2one ) Rabbit_ RNF20 ( ortholog_one2one ) |
| Ohnologs | RNF40 |
| Paralogs | RNF40 |
| Tissue | NA |
| Tissue Specificity | Expressed in the normal brain and also in malignant gliomas (at protein level). {ECO:0000269|PubMed:19037095}. |
| Pharmacological Animal Models | 0.022961(Chimpanzee);0.011588(Mouse);0.002190(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5TRB (X-ray 1.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19037095, ECO:0000305|PubMed:16337599}. |
| Mouse PG classification | NA |
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