| Gene Information | |
|---|---|
| Gene Name | TINF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 451 |
| Protein Names | TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000092330 ) 3 ( ENSG00000284915 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BSI4 |
| Gene Card | TINF2 |
| Uniprot ID | Q9BSI4 |
| Pfam | PF14973 |
| In ASD | no |
| Allosteric Prediction | yes (0.018765601) |
| Ortholog in Animals | Alpaca_ TINF2 ( ortholog_one2one ) Dog_ TINF2 ( ortholog_one2one ) Macaque_ TINF2 ( ortholog_one2one ) Mouse_ Tinf2 ( ortholog_one2one ) Pig_ TINF2 ( ortholog_one2one ) Rat_ Tinf2 ( ortholog_one2one ) Rabbit_ TINF2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002865(Rat);0.04944(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3BQO (X-ray 2.00A ) 3BU8 (X-ray 2.15A ) 5XYF (X-ray 2.20A ) |
| DBSNP | rs35653076 rs17102313 rs17102311 rs121918543 rs121918544 rs121918545 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19279399}. Chromosome, telomere {ECO:0000269|PubMed:19279399}. Note=Associated with telomeres.; [Isoform 1]: Nucleus matrix {ECO:0000269|PubMed:19229133}. |
| Mouse PG classification | NA |
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