| Gene Information | |
|---|---|
| Gene Name | DACH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 758 |
| Protein Names | Dachshund homolog 1 (Dach1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000276644 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UI36 |
| Gene Card | DACH1 |
| Uniprot ID | Q9UI36 |
| Pfam | PF02437 |
| In ASD | no |
| Allosteric Prediction | no (-0.083155464) |
| Ortholog in Animals | Alpaca_ DACH1 ( ortholog_one2one ) Dog_ DACH1 ( ortholog_one2one ) GuineaPig_ DACH1 ( ortholog_one2one ) Macaque_ DACH1 ( ortholog_one2one ) Mouse_ Dach1 ( ortholog_one2one ) Pig_ DACH1 ( ortholog_one2one ) Rat_ Dach1 ( ortholog_one2one ) Rabbit_ DACH1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DACH2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Isoform 2 is found in brain, heart, kidney, liver, leukocytes and spleen. Isoform 3 is found in liver and heart. Isoform 4 is found in spleen. {ECO:0000269|PubMed:11543628}. |
| Pharmacological Animal Models | 0.014963(Chimpanzee);0.021238(Mouse);0.002240(Rat);0.040000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1L8R (X-ray 1.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14525983}. |
| Mouse PG classification | NA |
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