| Gene Information | |
|---|---|
| Gene Name | TIMP |
| Organism | Homo sapiens (Human) |
| Gene Length | 207 |
| Protein Names | Metalloproteinase inhibitor 1 (Erythroid-potentiating activity) (EPA) (Fibroblast collagenase inhibitor) (Collagenase inhibitor) (Tissue inhibitor of metalloproteinases 1) (TIMP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P01033 |
| Gene Card | TIMP1 |
| Uniprot ID | P01033 |
| Pfam | PF00965 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in rheumatoid synovial fluid (at protein level). {ECO:0000269|PubMed:1730286}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.002240(Rat);0.050000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1D2B (NMR - ) 1OO9 (NMR - ) 1UEA (X-ray 2.80A ) 2J0T (X-ray 2.54A ) 3MA2 (X-ray 2.05A ) 3V96 (X-ray 1.90A ) 6MAV (X-ray 2.37A ) 6N9D (X-ray 2.67A ) 7S7L (X-ray 2.34A ) 7S7M (X-ray 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:1730286, ECO:0000269|PubMed:24635319, ECO:0000269|PubMed:3010309, ECO:0000269|PubMed:3839290, ECO:0000269|PubMed:3903517, ECO:0000269|PubMed:8541540}. |
| Mouse PG classification | NA |
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