| Gene Information | |
|---|---|
| Gene Name | TIE |
| Organism | Homo sapiens (Human) |
| Gene Length | 1138 |
| Protein Names | Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P35590 |
| Gene Card | TIE1 |
| Uniprot ID | P35590 |
| Pfam | PF00041; PF00047; PF07714 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in developing vascular endothelial cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5N06 (X-ray 2.50A ) |
| DBSNP | rs56302794 rs35573981 rs34993202 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:15851516, ECO:0000269|PubMed:20227369}; Single-pass type I membrane protein {ECO:0000269|PubMed:15851516, ECO:0000269|PubMed:20227369}. |
| Mouse PG classification | NA |
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