| Gene Information | |
|---|---|
| Gene Name | TIAF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2054 |
| Protein Names | Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q92614 |
| Gene Card | MYO18A |
| Uniprot ID | Q92614 |
| Pfam | PF00063; PF01576; PF17820 |
| In ASD | no |
| Allosteric Prediction | no (-1.213343356) |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8076604 |
| Subcellular location [CC] | Golgi apparatus {ECO:0000269|PubMed:19837035}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:19837035}. Golgi outpost {ECO:0000250|UniProtKB:D3ZFD0}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:D3ZFD0}. Note=Recruited to the Golgi apparatus by GOLPH3 (PubMed:19837035). Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). {ECO:0000250|UniProtKB:D3ZFD0, ECO:0000269|PubMed:19837035}.; [Isoform 1]: Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250|UniProtKB:Q9JMH9}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9JMH9}. Note=Colocalizes with actin. {ECO:0000250|UniProtKB:Q9JMH9}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:12761286}. Note=Lacks the PDZ domain (PubMed:12761286). Diffusely localized in the cytoplasm (PubMed:12761286). {ECO:0000269|PubMed:12761286}.; [Isoform 5]: Cell surface {ECO:0000269|PubMed:16087679}. |
| Mouse PG classification | NA |
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