| Gene Information | |
|---|---|
| Gene Name | THSD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 852 |
| Protein Names | Thrombospondin type-1 domain-containing protein 1 (Transmembrane molecule with thrombospondin module) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000136114 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NS62 |
| Gene Card | THSD1 |
| Uniprot ID | Q9NS62 |
| Pfam | PF00090 |
| In ASD | no |
| Allosteric Prediction | no (-1.205276537) |
| Ortholog in Animals | Alpaca_ THSD1 ( ortholog_one2one ) Dog_ THSD1 ( ortholog_one2one ) GuineaPig_ THSD1 ( ortholog_one2one ) Macaque_ THSD1 ( ortholog_one2one ) Mouse_ Thsd1 ( ortholog_one2one ) Pig_ THSD1 ( ortholog_one2one ) Rat_ Thsd1 ( ortholog_one2one ) Rabbit_ THSD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1380388780 rs13313279 rs9536062 rs776400380 rs201805081 rs56013270 rs141140186 rs1024014523 rs371717283 rs9536041 rs780150341 |
| Subcellular location [CC] | [Isoform 1]: Endosome membrane {ECO:0000269|PubMed:29069646}; Single-pass type I membrane protein {ECO:0000305}. Cell junction, focal adhesion {ECO:0000269|PubMed:29069646}. Note=Localizes to nascent focal adhesions. {ECO:0000269|PubMed:29069646}.; [Isoform 2]: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 3]: Secreted. |
| Mouse PG classification | NA |
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