| Gene Information | |
|---|---|
| Gene Name | CD36 |
| Organism | Homo sapiens (Human) |
| Gene Length | 472 |
| Protein Names | Platelet glycoprotein 4 (Fatty acid translocase) (FAT) (Glycoprotein IIIb) (GPIIIB) (Leukocyte differentiation antigen CD36) (PAS IV) (PAS-4) (Platelet collagen receptor) (Platelet glycoprotein IV) (GPIV) (Thrombospondin receptor) (CD antigen CD36) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000135218 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P16671 |
| Gene Card | CD36 |
| Uniprot ID | P16671 |
| Pfam | PF01130 |
| In ASD | no |
| Allosteric Prediction | yes (0.869455815) |
| Ortholog in Animals | Alpaca_ CD36 ( ortholog_one2one ) Dog_ CD36 ( ortholog_one2one ) GuineaPig_ CD36 ( ortholog_one2one ) Macaque_ CD36 ( ortholog_one2one ) Mouse_ Cd36 ( ortholog_one2one ) Rat_ RGD1565355 ( ortholog_one2one ) Rabbit_ CD36 ( ortholog_one2one ) |
| Ohnologs | SCARB1 |
| Paralogs | SCARB2, SCARB1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5LGD (X-ray 2.07A ) |
| DBSNP | rs75326924 rs183461468 rs201765331 rs5957 rs756525492 rs142186404 rs370072057 rs148910227 rs121918035 rs200771788 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16880211, ECO:0000269|PubMed:32958780}; Multi-pass membrane protein {ECO:0000255}. Membrane raft {ECO:0000269|PubMed:16880211}. Golgi apparatus {ECO:0000269|PubMed:16880211}. Apical cell membrane {ECO:0000250|UniProtKB:Q08857}. Note=Upon ligand-binding, internalized through dynamin-dependent endocytosis. {ECO:0000269|PubMed:20037584}. |
| Mouse PG classification | NA |
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