Gene Information
Gene NameTHOC7
OrganismHomo sapiens (Human)
Gene Length204
Protein NamesTHO complex subunit 7 homolog (Functional spliceosome-associated protein 24) (fSAP24) (Ngg1-interacting factor 3-like protein 1-binding protein 1) (NIF3L1-binding protein 1) (hTREX30)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000163634 )
Evolutionary StageEukaryota
AlphaFoldDBQ6I9Y2
Gene CardTHOC7
Uniprot IDQ6I9Y2
PfamPF05615
In ASDno
Allosteric Predictionno (-1.519852291)
Ortholog in AnimalsAlpaca_ THOC7 ( ortholog_one2one )
Dog_ THOC7 ( ortholog_one2one )
GuineaPig_ THOC7 ( ortholog_one2one )
Macaque_ THOC7 ( ortholog_one2one )
Mouse_ Thoc7 ( ortholog_one2one )
Pig_ THOC7 ( ortholog_one2one )
Rat_ Thoc7 ( ortholog_one2one )
Rabbit_ THOC7 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.043401(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7APK  (EM  3.30A 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:12951069}. Nucleus {ECO:0000269|PubMed:12951069, ECO:0000269|PubMed:19059247}. Nucleus speckle {ECO:0000305}. Note=Interaction with THOC5 is required for nuclear localization. {ECO:0000269|PubMed:19059247}.
Mouse PG classificationNA
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