| Gene Information | |
|---|---|
| Gene Name | ATP1B3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 279 |
| Protein Names | Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298) |
| Target Name | sodium/potassium transporting atpase subunits |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000069849 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P54709 |
| Gene Card | ATP1B3 |
| Uniprot ID | P54709 |
| Pfam | PF00287 |
| In ASD | no |
| Allosteric Prediction | yes (0.035717363) |
| Ortholog in Animals | Alpaca_ ATP1B3 ( ortholog_one2one ) Dog_ ATP1B3 ( ortholog_one2one ) Mouse_ Atp1b3 ( ortholog_one2one ) Rat_ AABR07070238.1 ( ortholog_one2many ) Rat_ Atp1b3 ( ortholog_one2many ) Rabbit_ ATP1B3 ( ortholog_one2one ) |
| Ohnologs | ATP1B4, ATP1B2, ATP4B, ATP1B1 |
| Paralogs | ATP1B2, ATP4B, ATP1B4, ATP1B1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Apical cell membrane {ECO:0000250|UniProtKB:Q63377}; Single-pass type II membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q63377}; Single-pass type II membrane protein {ECO:0000255}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Mouse PG classification | NA |
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