| Gene Information | |
|---|---|
| Gene Name | THG1L |
| Organism | Homo sapiens (Human) |
| Gene Length | 298 |
| Protein Names | Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Induced in high glucose-1) (IHG-1) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000113272 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9NWX6 |
| Gene Card | THG1L |
| Uniprot ID | Q9NWX6 |
| Pfam | PF04446; PF14413 |
| In ASD | no |
| Allosteric Prediction | no (-1.078868367) |
| Ortholog in Animals | Alpaca_ THG1L ( ortholog_one2one ) Dog_ THG1L ( ortholog_one2one ) GuineaPig_ THG1L ( ortholog_one2one ) Macaque_ THG1L ( ortholog_one2one ) Mouse_ Thg1l ( ortholog_one2one ) Pig_ THG1L ( ortholog_one2one ) Rat_ Thg1l ( ortholog_one2one ) Rabbit_ THG1L ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues. {ECO:0000269|PubMed:15459185}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3OTB (X-ray 2.95A ) 3OTC (X-ray 3.01A ) 3OTD (X-ray 2.28A ) 3OTE (X-ray 2.56A ) 7CV1 (X-ray 4.00A ) |
| DBSNP | rs201920319 rs2270812 rs1581444231 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15459185}. Mitochondrion outer membrane {ECO:0000305|PubMed:25008184}. |
| Mouse PG classification | NA |
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