Gene Information
Gene NameTHEMIS
OrganismHomo sapiens (Human)
Gene Length641
Protein NamesProtein THEMIS (Thymocyte-expressed molecule involved in selection)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000172673 )
3 ( ENSG00000275122 )
Evolutionary StageVertebrata
AlphaFoldDBQ8N1K5
Gene CardTHEMIS
Uniprot IDQ8N1K5
PfamPF12736
In ASDno
Allosteric Predictionno (-0.753918763)
Ortholog in AnimalsAlpaca_ THEMIS ( ortholog_one2one )
Dog_ THEMIS ( ortholog_one2one )
GuineaPig_ THEMIS ( ortholog_one2one )
Macaque_ THEMIS ( ortholog_one2one )
Mouse_ Themis ( ortholog_one2one )
Pig_ THEMIS ( ortholog_one2one )
Rat_ Themis ( ortholog_one2one )
Rabbit_ THEMIS ( ortholog_one2one )
OhnologsNA
ParalogsTHEMIS2
Tissueappendix, lymph.node, tonsil
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11968051  rs675531 
Subcellular location [CC]Cytoplasm {ECO:0000250|UniProtKB:Q8BGW0}. Nucleus {ECO:0000250|UniProtKB:Q8BGW0}.
Mouse PG classificationNA
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