Gene Information
Gene NameTHEM5
OrganismHomo sapiens (Human)
Gene Length247
Protein NamesAcyl-coenzyme A thioesterase THEM5 (Acyl-CoA thioesterase THEM5) (EC 3.1.2.2) (Acyl-coenzyme A thioesterase 15) (Thioesterase superfamily member 5)
Target NameNA
Target TypeNA
Gene Age244 ( ENSG00000196407 )
Evolutionary StageMammalia
AlphaFoldDBQ8N1Q8
Gene CardTHEM5
Uniprot IDQ8N1Q8
PfamPF03061
In ASDno
Allosteric Predictionno (-1.505829046)
Ortholog in AnimalsAlpaca_ THEM5 ( ortholog_one2one )
Dog_ THEM5 ( ortholog_one2one )
GuineaPig_ THEM5 ( ortholog_one2one )
Macaque_ THEM4 ( ortholog_one2one )
Mouse_ Them5 ( ortholog_one2one )
Pig_ THEM5 ( ortholog_one2one )
Rat_ Them5 ( ortholog_one2one )
Rabbit_ THEM5 ( ortholog_one2one )
OhnologsNA
ParalogsTHEM4
Tissueskin, zone.of.skin, lower.leg.skin, suprapubic.skin
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4AE7  (X-ray  1.45A 
DBSNP rs16833597  rs6587625  rs6587624 
Subcellular location [CC]Mitochondrion matrix {ECO:0000269|PubMed:22586271}.
Mouse PG classificationNA
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