| Gene Information | |
|---|---|
| Gene Name | CLK4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 481 |
| Protein Names | Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4) |
| Target Name | dual specificity protein kinase clk4 |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000113240 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HAZ1 |
| Gene Card | CLK4 |
| Uniprot ID | Q9HAZ1 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.21222751) |
| Ortholog in Animals | Alpaca_ CLK4 ( ortholog_one2one ) Dog_ CLK4 ( ortholog_one2one ) GuineaPig_ CLK4 ( ortholog_one2one ) Macaque_ CLK4 ( ortholog_one2one ) Mouse_ Clk4 ( ortholog_one2one ) Pig_ CLK4 ( ortholog_one2one ) Rat_ Clk4 ( ortholog_one2one ) Rabbit_ CLK4 ( ortholog_one2one ) |
| Ohnologs | CLK1 |
| Paralogs | CLK1, HIPK3, DYRK4, DYRK1B, HIPK1, CLK3, HIPK4, DYRK3, HIPK2, DYRK2, DYRK1A, CLK2 |
| Tissue | NA |
| Tissue Specificity | Expressed in liver, kidney, heart, muscle, brain and endothelial cells. {ECO:0000269|PubMed:11170754, ECO:0000269|PubMed:19168442}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 6FYV (X-ray 2.46A ) |
| DBSNP | rs35272416 rs55746655 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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