| Gene Information | |
|---|---|
| Gene Name | TIMP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 224 |
| Protein Names | Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000157150 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99727 |
| Gene Card | TIMP4 |
| Uniprot ID | Q99727 |
| Pfam | PF00965 |
| In ASD | no |
| Allosteric Prediction | no (-0.058494562) |
| Ortholog in Animals | Alpaca_ TIMP4 ( ortholog_one2one ) Dog_ TIMP4 ( ortholog_one2one ) GuineaPig_ TIMP4 ( ortholog_one2one ) Macaque_ TIMP4 ( ortholog_one2one ) Mouse_ Timp4 ( ortholog_one2one ) Pig_ TIMP4 ( ortholog_one2one ) Rat_ Timp4 ( ortholog_one2one ) Rabbit_ TIMP4 ( ortholog_one2one ) |
| Ohnologs | TIMP3, TIMP1 |
| Paralogs | TIMP1, TIMP2, TIMP3 |
| Tissue | adipose.tissue |
| Tissue Specificity | Abundant in heart and present at low levels in many other tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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