| Gene Information | |
|---|---|
| Gene Name | TGT |
| Organism | Homo sapiens (Human) |
| Gene Length | 494 |
| Protein Names | Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P54578 |
| Gene Card | USP14 |
| Uniprot ID | P54578 |
| Pfam | PF00443 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.056905(Chimpanzee);0.125683(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2AYN (X-ray 3.20A ) 2AYO (X-ray 3.50A ) 5GJQ (EM 4.50A ) 6IIK (X-ray 1.97A ) 6IIL (X-ray 2.20A ) 6IIM (X-ray 2.21A ) 6IIN (X-ray 2.53A ) 6LVS (X-ray 2.73A ) 7W37 (EM 3.00A ) 7W38 (EM 3.10A ) 7W39 (EM 3.20A ) 7W3A (EM 3.50A ) 7W3B (EM 3.60A ) 7W3C (EM 3.40A ) 7W3F (EM 3.30A ) 7W3G (EM 3.20A ) 7W3H (EM 3.20A ) 7W3I (EM 3.50A ) 7W3J (EM 3.50A ) 7W3K (EM 3.60A ) 7W3M (EM 3.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19106094}. Cell membrane {ECO:0000269|PubMed:19106094}; Peripheral membrane protein {ECO:0000269|PubMed:19106094}. |
| Mouse PG classification | NA |
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