| Gene Information | |
|---|---|
| Gene Name | TGR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 415 |
| Protein Names | Neuromedin-U receptor 2 (NMU-R2) (G-protein coupled receptor FM-4) (G-protein coupled receptor TGR-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9GZQ4 |
| Gene Card | NMUR2 |
| Uniprot ID | Q9GZQ4 |
| Pfam | PF00001; PF19285 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus. {ECO:0000269|PubMed:10887190, ECO:0000269|PubMed:10894543, ECO:0000269|PubMed:10899166, ECO:0000269|PubMed:11010960}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4958535 rs1895245 rs4958532 rs4958531 rs1363422 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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