| Gene Information | |
|---|---|
| Gene Name | TGM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 693 |
| Protein Names | Protein-glutamine gamma-glutamyltransferase E (EC 2.3.2.13) (Transglutaminase E) (TG(E)) (TGE) (TGase E) (Transglutaminase-3) (TGase-3) [Cleaved into: Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain] |
| Target Name | protein-glutamine gamma-glutamyltransferase e |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000125780 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q08188 |
| Gene Card | TGM3 |
| Uniprot ID | Q08188 |
| Pfam | PF00927; PF01841; PF00868 |
| In ASD | no |
| Allosteric Prediction | no (-0.326552741) |
| Ortholog in Animals | Alpaca_ TGM3 ( ortholog_one2one ) Dog_ TGM3 ( ortholog_one2one ) GuineaPig_ TGM3 ( ortholog_one2one ) Macaque_ TGM3 ( ortholog_one2one ) Mouse_ Tgm3 ( ortholog_one2one ) Pig_ TGM3 ( ortholog_one2one ) Rat_ Tgm3 ( ortholog_one2one ) Rabbit_ TGM3 ( ortholog_one2one ) |
| Ohnologs | TGM1, TGM5, TGM4 |
| Paralogs | TGM6, TGM5, TGM7, EPB42, TGM2, TGM4, TGM1, F13A1 |
| Tissue | esophagus, tongue, esophagus.mucosa |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1L9M (X-ray 2.10A ) 1L9N (X-ray 2.10A ) 1NUD (X-ray 2.70A ) 1NUF (X-ray 2.70A ) 1NUG (X-ray 2.40A ) |
| DBSNP | rs214803 rs6048066 rs214814 rs1042617 rs214830 rs45581032 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:27866708}. |
| Mouse PG classification | NA |
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