| Gene Information | |
|---|---|
| Gene Name | LIME1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 295 |
| Protein Names | Lck-interacting transmembrane adapter 1 (Lck-interacting membrane protein) (Lck-interacting molecule) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000203896 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9H400 |
| Gene Card | LIME1 |
| Uniprot ID | Q9H400 |
| Pfam | PF15332 |
| In ASD | no |
| Allosteric Prediction | no (-1.112096631) |
| Ortholog in Animals | Alpaca_ LIME1 ( ortholog_one2one ) Macaque_ LIME1 ( ortholog_one2one ) Mouse_ Lime1 ( ortholog_one2one ) Rat_ Lime1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TFIP11, ZGPAT |
| Tissue | NA |
| Tissue Specificity | Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level). {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046, ECO:0000269|PubMed:16160011}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1151625 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}; Single-pass type III membrane protein {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}. Note=Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell. |
| Mouse PG classification | NA |
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