| Gene Information | |
|---|---|
| Gene Name | TFAP2D |
| Organism | Homo sapiens (Human) |
| Gene Length | 452 |
| Protein Names | Transcription factor AP-2-delta (AP2-delta) (Activating enhancer-binding protein 2-delta) (Transcription factor AP-2-beta-like 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000008197 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q7Z6R9 |
| Gene Card | TFAP2D |
| Uniprot ID | Q7Z6R9 |
| Pfam | PF03299 |
| In ASD | no |
| Allosteric Prediction | no (-0.995635427) |
| Ortholog in Animals | Alpaca_ TFAP2D ( ortholog_one2one ) Dog_ TFAP2D ( ortholog_one2one ) GuineaPig_ TFAP2D ( ortholog_one2one ) Macaque_ TFAP2D ( ortholog_one2one ) Mouse_ Tfap2d ( ortholog_one2one ) Pig_ TFAP2D ( ortholog_one2one ) Rat_ Tfap2d ( ortholog_one2one ) Rabbit_ TFAP2D ( ortholog_one2one ) |
| Ohnologs | TFAP2C, TFAP2A, TFAP2E |
| Paralogs | TFAP2B, TFAP2A, TFAP2E, TFAP2C |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas. {ECO:0000269|PubMed:11733187}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |