| Gene Information | |
|---|---|
| Gene Name | TFAP2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 460 |
| Protein Names | Transcription factor AP-2-beta (AP2-beta) (Activating enhancer-binding protein 2-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000008196 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92481 |
| Gene Card | TFAP2B |
| Uniprot ID | Q92481 |
| Pfam | PF03299 |
| In ASD | no |
| Allosteric Prediction | yes (0.213867434) |
| Ortholog in Animals | Alpaca_ TFAP2B ( ortholog_one2one ) Dog_ TFAP2B ( ortholog_one2one ) GuineaPig_ TFAP2B ( ortholog_one2one ) Macaque_ TFAP2B ( ortholog_one2one ) Mouse_ Tfap2b ( ortholog_one2one ) Pig_ TFAP2B ( ortholog_one2one ) Rat_ Tfap2b ( ortholog_one2one ) Rabbit_ TFAP2B ( ortholog_one2one ) |
| Ohnologs | TFAP2C, TFAP2A, TFAP2E |
| Paralogs | TFAP2E, TFAP2A, TFAP2C, TFAP2D |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs80338910 rs80338912 rs80338912 rs80338914 rs80338915 rs80338917 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q61313}. Note=In the brain, localizes to the arcuate hypothalamic nucleus, the ventromedial hypothalamic nucleus and the accumbens nucleus of the ventral striatum. {ECO:0000250|UniProtKB:Q61313}. |
| Mouse PG classification | NA |
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