| Gene Information | |
|---|---|
| Gene Name | BCL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 454 |
| Protein Names | B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000069399 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P20749 |
| Gene Card | BCL3 |
| Uniprot ID | P20749 |
| Pfam | PF12796 |
| In ASD | no |
| Allosteric Prediction | yes (0.037245255) |
| Ortholog in Animals | Alpaca_ BCL3 ( ortholog_one2one ) Dog_ BCL3 ( ortholog_one2one ) GuineaPig_ BCL3 ( ortholog_one2one ) Macaque_ BCL3 ( ortholog_one2one ) Mouse_ Bcl3 ( ortholog_one2one ) Pig_ BCL3 ( ortholog_one2one ) Rat_ Bcl3 ( ortholog_one2one ) Rabbit_ BCL3 ( ortholog_one2one ) |
| Ohnologs | NFKBIA, NFKBIE |
| Paralogs | POTEH, POTEB2, POTED, POTEG, POTEB3, POTEM, POTEJ, POTEF, POTEB, POTEE, POTEI, POTEC, POTEA, NFKBIE |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1K1A (X-ray 1.86A ) 1K1B (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. {ECO:0000250}. |
| Mouse PG classification | NA |
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