| Gene Information | |
|---|---|
| Gene Name | MLZE |
| Organism | Homo sapiens (Human) |
| Gene Length | 508 |
| Protein Names | Gasdermin-C (Melanoma-derived leucine zipper-containing extranuclear factor) [Cleaved into: Gasdermin-C, N-terminal (GSDMC-NT); Gasdermin-C, C-terminal (GSDMC-CT)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BYG8 |
| Gene Card | GSDMC |
| Uniprot ID | Q9BYG8 |
| Pfam | PF04598; PF17708 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310). {ECO:0000269|PubMed:11223543, ECO:0000269|PubMed:19051310}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10090835 rs16904151 rs4144738 |
| Subcellular location [CC] | [Gasdermin-C]: Cytoplasm, cytosol {ECO:0000269|PubMed:11223543}.; [Gasdermin-C, N-terminal]: Cell membrane {ECO:0000250|UniProtKB:Q5Y4Y6}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5Y4Y6}. |
| Mouse PG classification | NA |
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