Gene Information
Gene NameUBXN2B
OrganismHomo sapiens (Human)
Gene Length331
Protein NamesUBX domain-containing protein 2B (NSFL1 cofactor p37) (p97 cofactor p37)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000215114 )
Evolutionary StageEukaryota
AlphaFoldDBQ14CS0
Gene CardUBXN2B
Uniprot IDQ14CS0
PfamPF08059; PF00789
In ASDno
Allosteric Predictionno (-1.453955151)
Ortholog in AnimalsAlpaca_ UBXN2B ( ortholog_one2one )
Dog_ UBXN2B ( ortholog_one2one )
GuineaPig_ UBXN2B ( ortholog_one2one )
Macaque_ UBXN2B ( ortholog_one2one )
Mouse_ Ubxn2b ( ortholog_one2one )
Pig_ UBXN2B ( ortholog_one2one )
Rat_ Ubxn2b ( ortholog_one2one )
Rabbit_ UBXN2B ( ortholog_one2one )
OhnologsNSFL1C, UBXN2A
ParalogsNSFL1C, UBXN2A, UBXN11
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.016289(Chimpanzee);0.009624(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000250|UniProtKB:P0C627}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P0C627}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P0C627}. Golgi apparatus {ECO:0000250|UniProtKB:P0C627}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q0KL01}. Note=Localizes to centrosome during mitotic prophase and metaphase. {ECO:0000250|UniProtKB:Q0KL01}.
Mouse PG classificationNA
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