| Gene Information | |
|---|---|
| Gene Name | KIAA1733 |
| Organism | Homo sapiens (Human) |
| Gene Length | 580 |
| Protein Names | Phosphatase and actin regulator 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9C0D0 |
| Gene Card | PHACTR1 |
| Uniprot ID | Q9C0D0 |
| Pfam | PF02755 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in umbilical vein endothelial cells. {ECO:0000269|PubMed:21939755}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ZEE (X-ray 1.90A ) 6ZEF (X-ray 1.94A ) 6ZEG (X-ray 1.09A ) 6ZEH (X-ray 1.30A ) 6ZEI (X-ray 1.39A ) 6ZEJ (X-ray 1.78A ) |
| DBSNP | rs17602409 rs1562103192 rs1562114406 rs748743403 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Synapse {ECO:0000250}. Nucleus {ECO:0000250}. Note=Enriched at synapses (By similarity). Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |