| Gene Information | |
|---|---|
| Gene Name | TENM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2699 |
| Protein Names | Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000218336 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9P273 |
| Gene Card | TENM3 |
| Uniprot ID | Q9P273 |
| Pfam | PF06484; PF15636 |
| In ASD | no |
| Allosteric Prediction | no (-1.407390729) |
| Ortholog in Animals | Alpaca_ TENM3 ( ortholog_one2one ) Dog_ TENM3 ( ortholog_one2one ) GuineaPig_ TENM3 ( ortholog_one2one ) Macaque_ TENM3 ( ortholog_one2one ) Mouse_ Tenm3 ( ortholog_one2one ) Pig_ TENM3 ( ortholog_one2one ) Rat_ Tenm3 ( ortholog_one2one ) Rabbit_ TENM3 ( ortholog_one2one ) |
| Ohnologs | TENM1, TENM2, TENM4 |
| Paralogs | TENM2, TENM4, TENM1, NAGPA |
| Tissue | NA |
| Tissue Specificity | Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nucleus, followed by thalamus and subthalamic nucleus. {ECO:0000269|PubMed:10625539, ECO:0000269|PubMed:10819331}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3749509 rs1243762658 rs755000701 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9WTS6}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9WTS6}. Cell projection, axon {ECO:0000250|UniProtKB:Q9WTS6}. |
| Mouse PG classification | LPG |
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