| Gene Information | |
|---|---|
| Gene Name | TEM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 757 |
| Protein Names | Endosialin (Tumor endothelial marker 1) (CD antigen CD248) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9HCU0 |
| Gene Card | CD248 |
| Uniprot ID | Q9HCU0 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts. {ECO:0000269|PubMed:10947988, ECO:0000269|PubMed:11084048, ECO:0000269|PubMed:1438285, ECO:0000269|PubMed:15862292, ECO:0000269|PubMed:16076089}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3741367 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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