| Gene Information | |
|---|---|
| Gene Name | TEC |
| Organism | Homo sapiens (Human) |
| Gene Length | 626 |
| Protein Names | Nuclear receptor subfamily 4 group A member 3 (Mitogen-induced nuclear orphan receptor) (Neuron-derived orphan receptor 1) (Nuclear hormone receptor NOR-1) |
| Target Name | tyrosine-protein kinase tec |
| Target Type | Patented-recorded target |
| Gene Age | 645 ( ENSG00000135605 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92570 |
| Gene Card | NR4A3 |
| Uniprot ID | Q92570 |
| Pfam | PF00104; PF00105 |
| In ASD | no |
| Allosteric Prediction | yes (0.157077895) |
| Ortholog in Animals | Alpaca_ TEC ( ortholog_one2one ) Dog_ TEC ( ortholog_one2one ) GuineaPig_ TEC ( ortholog_one2one ) Macaque_ TEC ( ortholog_one2one ) Mouse_ Tec ( ortholog_one2one ) Pig_ TEC ( ortholog_one2one ) Rat_ Tec ( ortholog_one2one ) Rabbit_ TEC ( ortholog_one2one ) |
| Ohnologs | BTK, ITK |
| Paralogs | FGR, FRK, JAK3, BMX, FER, BTK, FES, BLK, JAK1, PTK2B, SYK, TYK2, LYN, ZAP70, TXK, TNK2, PTK2, SRMS, CSK, STYK1, YES1, LCK, SRC, JAK2, ITK, MATK, TNK1, HCK, ABL1, ABL2, FYN, PTK6 |
| Tissue | NA |
| Tissue Specificity | Isoform alpha is highly expressed in skeletal muscle. Isoform beta is highly expressed in skeletal muscle and low expressed in fetal brain and placenta. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}. |
| Mouse PG classification | NA |
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